References

1. C. Manyi-Loh, S. Mamphweli, E. Meyer, A. Okoh, Antibiotic use in agriculture and its consequential resistance in environmental sources: potential public health implications, Molecules, 23 (2018) 1–48.
2. Y. Ben, C. Fu, M. Hu, L. Liu, M.H. Wong, C. Zheng, Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: a review, Environ. Res., 169 (2019) 483–493.
3. T.P. Van Boeckel, S. Gandra, A. Ashok, Q. Caudron, B.T. Grenfell, S.A. Levin, R. Laxminarayan, Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data, Lancet Infect. Dis., 14 (2014) 742–750.
4. T.P. Van Boeckel, C. Brower, M. Gilbert, B.T. Grenfell, S.A. Levin, T.P. Robinson, A. Teillant, R. Laxminarayan, Global trends in antimicrobial use in food animals, Proc. Natl. Acad. Sci. U.S.A., 112 (2015) 5649–5654.
5. R. Wise, Antimicrobial resistance: priorities for action, J. Antimicrob. Chemother., 49 (2002) 585–586.
6. K. Kümmerer, Antibiotics in the aquatic environment—a review-part 1, Chemosphere, 75 (2009a) 417–434.
7. U. Szymańska, M. Wiergowski, I. Sołtyszewski, J. Kuzemko, G. Wiergowska, M.K., Woźniak, Presence of antibiotics in the aquatic environment in Europe and their analytical monitoring: recent trends and perspectives, Microchem. J., 147 (2019) 729–740.
8. K.G. Karthikeyan, M.T. Meyer, Occurrence of antibiotics in wastewater treatment facilities in Wisconsin, USA, Sci. Total Environ., 361 (2006) 196–207.
9. M.C. Danner, A. Robertson, V. Behrends, J. Reiss, Antibiotic pollution in surface freshwaters: occurrence and effects, Sci. Total Environ., 664 (2019) 793–804.
10. L. Rizzo, C. Manaia, C. Merlin, T. Schwartz, C. Dagot, M.C. Ploy, I. Michael, D. Fatta-Kassinos, Urban wastewater treatment plants as hotspots for antibiotic-resistant bacteria and genes spread into the environment, Sci. Total Environ., 447 (2013) 345–360.
11. WHO, Antimicrobial Resistance, Report, World Health Organization, 2018. Available at: https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance
12. J. O’Neill, The Review on Antimicrobial Resistance, Antimicrobial Resistance, Tackling a Crisis for the Health and Wealth of Nations, 2016. Available at: https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf
13. V. Homem, L. Santos, Degradation and removal methods of antibiotics from aqueous matrices—a review, J. Environ. Manage., 92 (2011) 2304–2347.
14. K. Kümmerer, Antibiotics in the aquatic environment — a review, Part II, Chemosphere, 75 (2009b) 435–441.
15. N.H. Tran, H. Chen, M. Reinhard, F. Mao, K.Y.-H. Gin, Occurrence, and removal of multiple classes of antibiotics and antimicrobial agents in biological wastewater treatment processes, Water Res., 104 (2016) 461–472.
16. E. Felis, J. Kalka, A. Sochacki, K. Kowalska, S. Bajkacz, M. Harnisz, E. Korzeniewska, Antimicrobial pharmaceuticals in the aquatic environment - occurrence and environmental implications, Eur. J. Pharmacol., 866 (2020) 172813.
17. P. Krzemiński, M.C. Tomei, P. Karaolia, A. Langenhoff, C.M.R. Almeida, E. Felis, F. Gritten, H.R. Andersen, T. Fernandes, C.M. Manaia, L. Rizzo, D. Fatta-Kassinos, Performance of secondary wastewater treatment methods for the removal of contaminants of emerging concern implicated in crop uptake and antibiotic resistance spread: a review, Sci. Total Environ., 648 (2019) 1052–1081.
18. A. Osińska, E. Korzeniewska, M. Harnisz, E. Felis, S. Bajkacz, P. Jachimowicz, S. Niestępski, I. Konopka, Small-scale wastewater treatment plants as a source of the dissemination of antibiotic resistance genes in the aquatic environment, J. Hazard. Mater., 381 (2020) 121–221.
19. A.R. Ribeiro, B. Sures, T.C. Schmidt, Cephalosporin antibiotics in the aquatic environment: a critical review of occurrence, fate, ecotoxicity and removal technologies, Environ. Pollut., 241 (2018) 1153–1166.
20. R. Loos, D. Marinov, I. Sanseverino, D. Napierska, T. Lettieri, Review of the 1st Watch List Under the Water Framework Directive and Recommendations for the 2nd Watch List, JRC Technical Report, Publications Office of the European Union, 2018. Available at: https://doi.org/10.2760/614367
21. M. Kumar, S. Jaiswal, K.K. Sodhi, P. Shree, D.K. Singh, P.K. Agrawal, P. Shukla, Antibiotics bioremediation: perspectives on its ecotoxicity and resistance, Environ. Int., 124 (2019) 448–461.
22. EU Decision 2015/495 of 20 March 2015 Establishing a Watch List of Substances for Union-Wide Monitoring in the Field of Water Policy, Journal of the European Union, 2015.
23. EU Decision 2018/840 of 5 June 2018 Establishing a Watch List of Substances for Union-Wide Monitoring in the Field of Water Policy, Journal of the European Union, 2018.
24. M.P. Schlüsener, M. Spiteller, K. Bester, Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography–tandem mass spectrometry, J. Chromatogr. A, 1003 (2003) 21–28.
25. M.P. Schlüsener, K. Bester, M. Spiteller, Determination of antibiotics such as macrolides, ionophores, and tiamulin in liquid manure by HPLC–MS/MS, Anal. Bioanal. Chem., 375 (2003) 942–947.
26. M. Hijosa-Valsero, G. Fink, M.P. Schlüsener, R. Sidrach-Cardona, J. Martín-Villacorta, T. Ternes, E. Bécares, Removal of antibiotics from urban wastewater by constructed wetland optimization, Chemosphere, 83 (2011) 713–719.
27. P. Verlicchi, M. Al Aukidy, A. Galletti, M. Petrovic, D. Barceló, Hospital effluent: investigation of the concentrations and distribution of pharmaceuticals and environmental risk assessment, Sci. Total Environ., 430 (2012) 109–118.
28. M.J. Shreve, R.A. Brennan, Trace organic contaminant removal in six full-scale integrated fixed-film activated sludge (IFAS) systems treating municipal wastewater, Water Res., 151 (2019) 318–331.
29. M. Östman, R.H. Lindberg, J. Fick, E. Björn, M. Tysklind, Screening of biocides, metals, and antibiotics in swedish sewage sludge and wastewater, Water Res., 115 (2017) 318–328.
30. B. Li, T. Zhang, Mass flows and removal of antibiotics in two municipal wastewater treatment plants, Chemosphere, 83 (2011) 1284–1289.
31. F.A. Kibuye, H.E. Gall, K.R. Elkin, B. Ayers, T.L. Veith, M. Miller, S. Jacob, K.R. Hayden, J.E. Watson, H.A. Elliott, Fate of pharmaceuticals in a spray-irrigation system: from wastewater to groundwater, Sci. Total Environ., 654 (2019) 197–208.
32. R. Loos, R. Carvalho, D.C. António, S. Comero, G. Locoro, S. Tavazzi, B. Paracchini, M. Ghiani, T. Lettieri, L. Blaha, B. Jarosova, S. Voorspoels, K. Servaes, P. Haglund, J. Fickd, R.H. Lindberg, D. Schwesig, B.M. Gawlik, EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents, Water Res., 47 (2013) 6475–6487.
33. V. Licul-Kucera, M. Ladányi, G. Hizsnyik, G. Záray, V.G. Mihucz, A filtration optimized on-line SPE–HPLC–MS/MS method for determination of three macrolide antibiotics dissolved and bound to suspended solids in surface water, Microchem. J., 148 (2019) 480–492.
34. T. Ternes, A. Joss, Human Pharmaceuticals, Hormones and Fragrances - The Challenge of Micropollutants in Urban Water Management,IWA Publishing, 2006.